VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Pig

Scientific Name: Sus scrofa domestica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Artiodactyla-> Suina-> Suidae-> Sus-> Sus scrofa

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Foot-and-mouth disease virus

Family: Picornaviridae

Receptor: ITGAV

Receptor ITGAV information

Summary: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0046 2021.04 10X Genomics Lung Normal 21981 Link
Vthunter_0069 2021.04 10X Genomics Frontal Normal 8812 Link
Vthunter_0070 2021.04 10X Genomics Occipital Normal 6829 Link
Vthunter_0071 2021.04 10X Genomics Parietal Normal 6162 Link
Vthunter_0072 2021.04 10X Genomics Hypothalamus Normal 7302 Link
Vthunter_0073 2021.04 10X Genomics Temporal Normal 3145 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_1013 2019.12 10X Genomics Lung Normal 7465 Link
Vthunter_1014 2019.12 10X Genomics Lung Normal 3987 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of ITGAV in human tissues   [NCBI]

Expression: Ubiquitous expression in thyroid (RPKM 45.9), ovary (RPKM 36.3) and 24 other tissues

Protein expression of ITGAV in human tissues   [Proteinatlas]